• Jump to content
  • Jump to navigation
  • Jump to bottom of page
Simulate organization breadcrumb open Simulate organization breadcrumb close
Pattern Recognition Lab
  • FAUTo the central FAU website
  • Campo
  • UnivIS
  • Jobs
  • Map
  • Help

Pattern Recognition Lab

Navigation Navigation close
  • Overview
    • Contact
    • Directions
    Portal Overview
  • Team
    • Former PRL members
    Portal Team
  • Research
    • Research Groups
    • Research Projects
    • Pattern Recognition Blog
    • Beyond the Patterns
    • Publications
    • Research Demo Videos
    • Datasets
    • Competitions
    Portal Research
  • Teaching
    • Curriculum / Courses
    • Lecture Notes
    • Lecture Videos
    • Thesis / Projects
    • Free Machine and Deep Learning Resources
    • Free Medical Engineering Resources
    • LME Videos
    Portal Teaching
  • Lab
    • News
    • Ph.D. Gallery
    • Cooperations
    • Join the Pattern Recognition Lab
    Portal Lab
  1. Home
  2. Research
  3. Research Groups
  4. Ophthalmic Imaging
  5. Joint Iterative Reconstruction and Motion Compensation for Optical Coherence Tomography Angiography

Joint Iterative Reconstruction and Motion Compensation for Optical Coherence Tomography Angiography

In page navigation: Research
  • Beyond the Patterns
  • Competitions
  • Publications
  • Datasets

Joint Iterative Reconstruction and Motion Compensation for Optical Coherence Tomography Angiography

Joint Iterative Reconstruction and Motion Compensation for Optical Coherence Tomography
Angiography

(Third Party Funds Single)

Titel des Gesamtprojektes:
Projektleitung: Andreas Maier, Stefan Ploner
Projektbeteiligte: Andreas Maier, Stefan Ploner, Lennart Husvogt
Projektstart: August 1, 2017
Projektende: July 31, 2019
Akronym: Joint Reco & MoCo for OCT(A)
Mittelgeber: DFG-Einzelförderung / Sachbeihilfe (EIN-SBH)
URL:

Abstract

Optical coherence tomography (OCT) is a non-invasive 3-D optical imaging
modality that is a standard of care in ophthalmology [1,2]. Since the introduction of Fourier-domain OCT [3], dramatic increases in imaging speed
became possible, enabling 3-D volumetric data to be acquired. Typically, a
region of the retina is scanned line by line, where each scanned line
acquires a cross-sectional image or a B-scan. Since B-scans are acquired
in milliseconds, slices extracted along a scan line, or the fast scan
axis, are barely affected by motion. In contrast, slices extracted
orthogonally to scan lines, i. e. in slow scan direction, are
affected by various types of eye motion occurring throughout the full,
multi-second volume acquisition time. The most relevant types of eye
movements during acquisition are (micro-)saccades, which can introduce
discontinuities or gaps between B-scans, and slow drifts, which cause
small, slowly changing distortion [4]. Additional eye motion is caused by pulsatile blood flow,
respiration and head motion. Despite ongoing advances in instrument
scanning speed [5,6] typical volume acquisition times have
not decreased. Instead, the additional scanning speed is used for dense
volumetric scanning or wider fields of view [7]. OCT angiography (OCTA) [8–11] multiplies the
required number of scans by at least two, and even more scans are needed
to accommodate recent developments in blood flow speed estimation which
are based on multiple interscan times [12,13]. As a consequence,
there is an ongoing need for improvement in motion compensation especially
in pathology [14–16].

We develop novel methods for retrospective motion correction of OCT volume scans of the anterior and posterior eye, and widefield imaging. Our algorithms are clinically usable due to their suitability for patients with limited fixation capabilities and increased amount of motion, due to their fast processing speed, and their high accuracy, both in terms of alignment and motion correction. By merging multiple accurately aligned scans, image quality can be increased substantially, enabling the inspection of novel features.

Publikationen

  • Kraus M., Moult EM., Yasin Alibhai A., Waheed NK., Duker JS., Fujimoto JG., Maier A., Ploner S., Husvogt L., Schottenhamml J.:
    Efficient and high accuracy 3-D OCT angiography motion correction in pathology
    In: Biomedical Optics Express 12 (2021), p. 125-146
    ISSN: 2156-7085
    DOI: 10.1364/BOE.411117
    URL: https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-12-1-125
    BibTeX: Download
  • Chen S., Schottenhamml J., Alibhai AY., Moult E., Waheed NK., Fujimoto JG., Maier A., Ploner S., Stromer D., Husvogt L.:
    Maximum a posteriori signal recovery for optical coherence tomography angiography image generation and denoising
    In: Biomedical Optics Express 12 (2021), p. 55-68
    ISSN: 2156-7085
    DOI: 10.1364/BOE.408903
    URL: https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-12-1-55&id=444277
    BibTeX: Download
  • Moult EM., Chen S., Novais E., Duker JS., Waheed NK., Fujimoto JG., Maier A., Ploner S., Husvogt L., Schottenhamml J.:
    OCT-OCTA segmentation: Combining structural and blood flow information to segment bruch's membrane
    In: Biomedical Optics Express 12 (2021), p. 84-99
    ISSN: 2156-7085
    DOI: 10.1364/BOE.398222
    BibTeX: Download
  • Moult EM., Alibhai AY., Rebhun CB., Lee B., Ploner S., Schottenhamml J., Husvogt L., Baumal CR., Witkin AJ., Maier A., Duker JS., Rosenfeld P., Waheed NK., Fujimoto JG.:
    Spatial Distribution of Choriocapillaris Impairment in Eyes with Choroidal Neovascularization Secondary to Age-Related Macular Degeneration
    In: Retina-The Journal of Retinal and Vitreous Diseases (2019)
    ISSN: 0275-004X
    DOI: 10.1097/IAE.0000000000002556
    URL: https://journals.lww.com/retinajournal/Abstract/publishahead/SPATIAL_DISTRIBUTION_OF_CHORIOCAPILLARIS.96058.aspx
    BibTeX: Download
  • Ploner S., Kraus MF., Husvogt L., Moult EM., Alibhai AY., Schottenhamml J., Geimer T., Rebhun CB., Lee B., Baumal CR., Waheed NK., Duker JS., Fujimoto JG., Maier A.:
    3-D OCT Motion Correction Efficiently Enhanced with OCT Angiography
    ARVO annual meeting 2018
    In: Investigative Ophthalmology & Visual Science 2018
    Open Access: https://iovs.arvojournals.org/article.aspx?articleid=2694583
    URL: https://iovs.arvojournals.org/article.aspx?articleid=2694583
    BibTeX: Download
Friedrich-Alexander-Universität
Erlangen-Nürnberg

Schlossplatz 4
91054 Erlangen
  • Login
  • Intranet
  • Imprint
  • Privacy
  • Accessibility
Up