Joint Iterative Reconstruction and Motion Compensation for Optical Coherence Tomography Angiography
Joint Iterative Reconstruction and Motion Compensation for Optical Coherence Tomography
Angiography
(Third Party Funds Single)
Titel des Gesamtprojektes:
Projektleitung: ,
Projektbeteiligte: , ,
Projektstart: August 1, 2017
Projektende: July 31, 2019
Akronym: Joint Reco & MoCo for OCT(A)
Mittelgeber: DFG-Einzelförderung / Sachbeihilfe (EIN-SBH)
URL:
Abstract
Optical coherence tomography (OCT) is a non-invasive 3-D optical imaging
modality that is a standard of care in ophthalmology [1,2]. Since the introduction of Fourier-domain OCT [3], dramatic increases in imaging speed
became possible, enabling 3-D volumetric data to be acquired. Typically, a
region of the retina is scanned line by line, where each scanned line
acquires a cross-sectional image or a B-scan. Since B-scans are acquired
in milliseconds, slices extracted along a scan line, or the fast scan
axis, are barely affected by motion. In contrast, slices extracted
orthogonally to scan lines, i. e. in slow scan direction, are
affected by various types of eye motion occurring throughout the full,
multi-second volume acquisition time. The most relevant types of eye
movements during acquisition are (micro-)saccades, which can introduce
discontinuities or gaps between B-scans, and slow drifts, which cause
small, slowly changing distortion [4]. Additional eye motion is caused by pulsatile blood flow,
respiration and head motion. Despite ongoing advances in instrument
scanning speed [5,6] typical volume acquisition times have
not decreased. Instead, the additional scanning speed is used for dense
volumetric scanning or wider fields of view [7]. OCT angiography (OCTA) [8–11] multiplies the
required number of scans by at least two, and even more scans are needed
to accommodate recent developments in blood flow speed estimation which
are based on multiple interscan times [12,13]. As a consequence,
there is an ongoing need for improvement in motion compensation especially
in pathology [14–16].
We develop novel methods for retrospective motion correction of OCT volume scans of the anterior and posterior eye, and widefield imaging. Our algorithms are clinically usable due to their suitability for patients with limited fixation capabilities and increased amount of motion, due to their fast processing speed, and their high accuracy, both in terms of alignment and motion correction. By merging multiple accurately aligned scans, image quality can be increased substantially, enabling the inspection of novel features.
Publikationen
Efficient and high accuracy 3-D OCT angiography motion correction in pathology
In: Biomedical Optics Express 12 (2021), p. 125-146
ISSN: 2156-7085
DOI: 10.1364/BOE.411117
URL: https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-12-1-125
BibTeX: Download
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Maximum a posteriori signal recovery for optical coherence tomography angiography image generation and denoising
In: Biomedical Optics Express 12 (2021), p. 55-68
ISSN: 2156-7085
DOI: 10.1364/BOE.408903
URL: https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-12-1-55&id=444277
BibTeX: Download
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OCT-OCTA segmentation: Combining structural and blood flow information to segment bruch's membrane
In: Biomedical Optics Express 12 (2021), p. 84-99
ISSN: 2156-7085
DOI: 10.1364/BOE.398222
BibTeX: Download
, , , , , , , , , :
Spatial Distribution of Choriocapillaris Impairment in Eyes with Choroidal Neovascularization Secondary to Age-Related Macular Degeneration
In: Retina-The Journal of Retinal and Vitreous Diseases (2019)
ISSN: 0275-004X
DOI: 10.1097/IAE.0000000000002556
URL: https://journals.lww.com/retinajournal/Abstract/publishahead/SPATIAL_DISTRIBUTION_OF_CHORIOCAPILLARIS.96058.aspx
BibTeX: Download
, , , , , , , , , , , , , :
3-D OCT Motion Correction Efficiently Enhanced with OCT Angiography
ARVO annual meeting 2018
In: Investigative Ophthalmology & Visual Science 2018
Open Access: https://iovs.arvojournals.org/article.aspx?articleid=2694583
URL: https://iovs.arvojournals.org/article.aspx?articleid=2694583
BibTeX: Download
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